Principal Scientist Early Discovery, Non Clinical Safety Lead

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Nonclinical Safety

Job Category:
Scientific/Technology

All Job Posting Locations:
San Diego, California, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Johnson & Johnson Innovative Medicine R&D is recruiting for a Principal Scientist Early Discovery, Non Clinical Safety Lead.

This position is a hybrid role and will be located in San Diego, California.

As a Principal Scientist Early Discovery, Non Clinical Safety Lead, you will collaborate with innovative and diverse scientists to support projects in our large and varied portfolio that spans multiple therapeutic areas and includes innovative modalities.  In this vital role you will provide toxicology leadership for all aspects of discovery and development projects, with flexibility to specialize or work across stages of development, therapy areas, and modalities.  You will also collaborate with discovery scientists to identify and nominate candidate molecules, and with development teams bring these molecules to humans and ultimately through global registration.

Principal Responsibilities:


* Lead in the application and design of Ai/ML based platform technologies to assess biology and molecule-based risk working with colleagues in Therapeutic discovery, Data Science and IT.


* Analyze results of in silico, in vitro and in vivo toxicology as well as of safety pharmacology studies and literature data, apply strategic perspective to results, and compile nonclinical safety assessments with a focus on translation for patients


* Represent PSTS on global discovery project teams, serving as a critical point of contact to the project team for safety, toxicology expertise and guidance


* Lead the early team of nonclinical safety, PK , bioanalytical, pathobiology, and in vivo scientists (PSTS team) working on a project.

 Ensure the smooth transfer of necessary information to functional areas within PSTS in conjunction with the PSTS team.


* Collaborate with multi...