Senior Science / People Lead in Bioconjugation and Protein Engineering (m/f/d)

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The Position

The Position

In Roche's Pharmaceutical Research and Early Development organization (pRED), we create transformative medicines for patients to address some of the world's most challenging unmet healthcare needs.

At pRED, we are united by our mission to transform science into medicines.

Together, we foster a culture defined by curiosity, responsibility, and humility, empowering our talented people to deliver life changing innovation with excellence and speed.

The position is located in Biological Core Technologies, a department within the Discovery of the pREDs Large Molecules Research , where the design, supply and development of next generation biologics is the primary focus.

We closely collaborate with our therapeutic areas and functions to convert therapeutic hypotheses into innovative therapeutics.

Job Mission

We are seeking a strategic leader and ADC subject matter expert to drive the next evolution of our protein therapeutics pipeline.

In this pivotal role, you will take full ownership of our bioconjugation and antibody discovery programs, directing a high-caliber team of specialists through the intricacies of early-stage drug development.

You won't just oversee strategies; you will architect the bioconjugation frameworks and protein engineering breakthroughs that define our future therapeutic portfolio through high-impact internal and external collaborations.

Your Impact


* Strategic Leadership: Lead and scale a high-performing team of 6–9 specialists in molecular biology and protein chemistry.

You will be responsible for their technical growth, resource allocation, and the delivery of critical project milestones.


* ADC & Bioconjugation Mastery: Serve as the primary architect for our ADC development strategies.

You will oversee both high-throughput automated and bespoke manual conjugation workflows, ensuring the successful translation of early discovery concepts into robust therapeutic candidates.


* Portfolio Acceleration: Drive innovation in antibody discovery and next-generation engineered proteins.

You will bridge the gap between initial protein design and clinical viability, leveraging your deep understanding of drug-to-antibody ratios (DAR), linker-payload chemistry, and analytical characterization.


* Global Influence: Act as a key technical representative in global partnerships, negotiating and managing complex collaborations to expand our technological capabilities.

Your Profile


* Proven Leadership: Extensive experience (5+ yea...