Senior Scientist Chemistry (m/f/d) in Chemistry R&D Diagnostics with focus on Oligonucleotide synthe

At Roche you can show up as yourself, embraced for the unique qualities you bring.

Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.

This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

Join Roche, where every voice matters.

The Position

A healthier future.

It’s what drives us to innovate.
To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That’s what makes us Roche. 

We create chemistry! Based on modern analytical methods and synthesis procedures we design and develop a great variety of chemical assay components for Dia and Pharma.

With our domain knowledge and our wide spectrum of methods, we also accompany the whole lifecycle of active diagnostics ingredients.

We provide in “Chemistry Technologies” a full spectrum of chemical technologies from small molecules to biooligomers and polymers to find the right solutions for diagnostic questions and beyond.

We design tailor-made molecules and develop lab scale procedures to provide a competitive advantage for our products.  

Your Key Responsibilities


* Development of synthesis strategies within projects that require particularly complex nucleic acid chemical and organic syntheses


* Conducting these syntheses in the laboratory


* Observing the field of nucleic acid chemistry and modern preparative organic chemistry through literature and patent studies, and attending conferences


* Building and maintaining a network through contacts with external and internal experts


* Collaborating with cooperating partners, e.g., in the USA


* Ensuring the required technology through the generation of own IP


* Adhering to internal and external regulations regarding occupational safety and environmental protection, quality management, labor law, confidentiality, etc.


* Representing the team leadership at project meetings and assisting in the professional supervision of employees

Who you are


* You have completed a university degree in chemistry and additionally a PhD in the field of organic chemistry


* You are an expert in oligonucleotide synthesis and preparative organic synthesis as well as in the purification of synthesis products.

You gained this special knowledge by working in the pharmaceutical industry for at least 3 -5 years. 


* Ideally, you have experience with non-standard oligo building blocks and ultra high purity reagents for the synthesis of highly pure oligonucleotides and experience with large scale, high quality oligonucleotide synthesis


* At the same time, you bring good knowledge in nucleic acids, excellent chemical knowledge, and basic knowl...