Clinical Pharmacology Leader

At Roche you can show up as yourself, embraced for the unique qualities you bring.

Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.

This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

Join Roche, where every voice matters.

The Position

In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.

At pRED, we are united by our mission to transform science into medicine.

Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

pRED's Pharmaceutical Sciences (PS) group enables discovery and development of safe and effective therapeutics at optimal doses in relevant populations with a vision to power translation, continuously improve the accuracy of our predictions and accelerate the development of tomorrow's medicines.

PS supports discovery and development across the whole value chain from target assessment to on-market and beyond.

In the Translational PKPD and Clinical Pharmacology chapter, our purpose is to select the right drug, to deliver the right dose and dosing schedule to patients to provide a meaningful benefit through strong collaboration, strategic thinking and regulatory and scientific excellence.

The Opportunity

The Clinical Pharmacology Leader (CPL) is a key member of the development teams, responsible for developing and executing the clinical pharmacology strategy for novel therapeutics from early-stage research through to post-marketing.

This role requires a strong scientific background in Clinical Pharmacology, strategic thinking, excellent communication and leadership skills.

The CPL works cross-functionally with various teams, including but not limited to discovery research & non-clinical functions, clinical science, clinical biomarker, clinical operations, biometrics & data science, and regulatory affairs, to ensure the clinical pharmacology aspects of drug development are robust and aligned with the overall project goals.

Key Responsibilities:



* You lead the clinical pharmacology strategy: develop,  implement and execute the clinical pharmacology plan for drug development projects, including but not limited to quantitative clinical pharmacology, dose selection, drug-drug interaction (DDI), formulation & device development and special population studies (e.g., renal impairment, hepatic impairment).


* You contribute to clinical trial design (from Phase 1 to Phase 3): provide expert input on clinical trial protocols, data analysis plans, and clinical study reports.

Responsible and accountable fo...