Scientist, DNA-Encoded Library Selections

At Roche you can show up as yourself, embraced for the unique qualities you bring.

Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.

This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

Join Roche, where every voice matters.

The Position

A healthier future.

It’s what drives us to innovate.

To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That’s what makes us Roche.

In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.

At pRED, we are united by our mission to transform science into medicine.

Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

The Therapeutic Modalities (TMo) function is part of the Roche Pharma Research and Early Development (pRED) organization.

TMo discovers and optimizes innovative drug candidates, including small molecules, biologics and nucleic acid-based therapeutics in order to deliver novel therapeutic approaches across all pRED Discovery and Translational areas (DTAs).

The DELT team lies within the Lead Discovery (LD) Department in Small Molecule Research, which is part of Therapeutic Modalities (TMo) within Roche Pharma Research and Early Development (pRED).

We deliver leading-edge science to drive the success of Roche’s early pipeline discovery research activities through a strong expertise in high-throughput or focused screening platforms, DNA-encoded library technology (DELT), protein science & enzymology/biophysics, cell-based assays and biostructure determination.

We are accountable for the provision of high-quality chemistry starting points for small-molecule projects and generating molecular and mechanistic insights that are critical for the advancement of discovery projects.

 

The Opportunity

We are offering a position as a Selection Scientist within the DNA-encoded library technology (DELT) team at the Roche Innovation Center Basel, Switzerland.

You will be responsible for leading and executing selections as part of the  global DELT platform at Roche, collaborating with project groups from all Roche R&D centers, and pushing the frontier of selection methodology to enable DELT screening regardless of  the target class, and collaborating closely with a multitude of disciplines across small molecule research.

You will also be expected to lead developments in automation and new selection techniques, integrate new modalities, and...