Senior Scientist, Translational PK/PD

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Pharmacokinetics & Pharmacometrics

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist, Translational PK/PD to be located in Spring House, PA.

A pre-identified candidate for consideration has been identified.

However, all applications will be considered.

Purpose: We are looking for a Translational PK/PD scientist to join our Translational Pharmacokinetics, Pharmacodynamics and Investigational Toxicology (TPPIT) group, part of Preclinical Sciences and Translational Safety (PSTS) organization.

This position will be responsible for serving as a translational PK/PD representative on project team , contribute towards driving Non-Clinical PK, ADME and PK/PD strategy and execution to enable timely recommendations for discovery programs, drive preclinical development through IND/CTA filing.

Using both experimental and computational tools, this individual will contribute towards relevant forward and reverse translation for projects and platform efforts.

You will be responsible for:


* Represent function and provide translational PK/PD support on project teams starting from early discovery through IND/CTA   


* Demonstrates fundamental knowledge of PK/ADME concepts  and conducts PK/PD data analysis to inform FIH dose selection and efficacious dose projections, design relevant experiment and modeling strategy, and integrate PK/ADME/PD data with pharmacology and toxicology profiles to effectively inform program strategy and decisions.


* Collaborate closely with biologists, chemists, protein engineers, toxicologists, bioanalytical scientists, clinical pharmacologists and clinicians to advance portfolio programs


* With oversight, author relevant sections of internal and regulatory submission documents and reports.

Qualifications:

Education:


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