Associate Scientist, Discovery Chemistry

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Chemical Research

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Associate Scientist, Discovery Chemistry.

A pre-identified candidate for consideration has been identified.

However, all applications will be considered.

Purpose: We are seeking an experienced, highly skilled, and motivated analytical and separation scientist to join our team in Spring House, PA as an Associate Scientist in Discovery Chemistry.

In this laboratory-based position, the successful candidate will provide high throughput purification to support medicinal chemistry efforts, with a particular emphasis on peptide projects.

This includes purifying compounds from focused chemical libraries or singleton samples at µg to grams using various techniques, such as mass-directed reversed-phase high performance liquid chromatography (RP-HPLC).

The candidate will work closely with scientists from Discovery Chemistry and Discovery Process Research to expedite compound design-synthesis-test iterations.

Strong communication skills and the ability to thrive in a team-oriented, results-driven environment are essential.

Additionally, the candidate must possess strong interpersonal skills to influence collaboration in a multidisciplinary setting.

You will be responsible for:


* Develop, implement, operate, optimize, and maintain efficient workflows and instrumentations in a highly automated setting for the analysis and purification of compounds from medicinal chemistry projects, particularly in peptide synthesis singletons and libraries utilizing RP-HPLC.


* Conduct high-throughput purification work, including crude sample method screening, purification, quality control, and distribution of purified samples specifically for peptide applications using reversed-phase HPLC.


* Optimize workflows for maxi...