Senior Scientist, Downstream Processing

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
Malvern, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for Senior Scientist, Downstream Processing to be in Malvern, PA.

Purpose:This position will lead and perform purification process development for the antibody-based modalities within the API-Large Molecule group in Malvern, PA.

Primary responsibilities will include leading and participating in the design of experiments, executing the planned experiments, and optimizing the process steps to the target process scale.

This will include laboratory and occasional pilot-scale scale chromatography and filtration.

The candidate will lead the design and execution of development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification and separation and several types of filtration.

The candidate will record and analyze experimental data, verify data integrity and accuracy, interpret analytical characterization results, and report/summarize findings to the project team, and also draft technical documents and perform technology transfer to collaboration partners.

The candidate should have experience with computational modeling/simulations and knowledge of downstream application.

The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objectives.

You will be responsible for:


* Lead and perform process development for the antibody purification processes.


* Lead, design and execute planned experiments which will include laboratory and occasional pilot-scale chromatography and filtration.


* Lead, design and execute development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification & separation and...