PostDoc Position in Extracellular Vesicle Biology (m/f/d)

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This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

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The Position

We are looking for a highly motivated and talented Postdoctoral Fellow (m/f/d) to join our Discovery Sciences team.

In this role you will be at the forefront of Science, enriching and analyzing Extracellular Vesicles (EVs) in order to deduce a diagnostic potential and address different medical needs.

Your responsibilities will encompass the design, execution, and analysis of wet-lab experiments.

This position is embedded within the Discovery Sciences Chapter at Roche Diagnostics GmbH.

As part of the Technology Program, you will join a high-impact team of researchers dedicated to pioneering next-generation diagnostic solutions. 

Our culture is defined by trust, transparency, and a strong collaborative spirit.

We are looking for a proactive colleague who balances independent critical thinking with team spirit and the flexibility to collaborate across diverse departments and interdisciplinary teams. 

Your tasks



* Perform the enrichment of EVs from human matrices, predominantly via immunoprecipitation, but also other methods like SEC, dUC and AF4.


* Analysis and quality assessment of the enriched EVs with different state-of-the-art methods and technologies (targeted and untargeted like mass spectrometry, RNA sequencing, luminescence) in cooperation with other departments


* Partner with bioinformatics, assay development, and sequencing teams to evaluate the applicability of the captured EVs for diagnostic platforms. 


* Drive interdisciplinary meetings to share data, leverage expertise across functions, and contribute to the broader Diagnostics strategy.


* Document findings for patent filings and present research in stakeholder meetings, scientific journals, and international conferences.

Your profile



* You have successfully completed a PhD in Molecular Biology, Biochemistry, Cell Biology or a related field including 3+ years of experimental research experience and a strong track record of peer-reviewed publications.


* You have deep expertise in the biology, enrichment and analysis of Extracellular Vesicles as well as the respective laboratory techniques, such as immunoprecipitation, size exclusion chromatography, asymmetrical flow field-flow fractionation, and immunoassays like ELISA and Western Blot, 


* Your profile is complemented by proficiency in working with nucleic acids like RNA isolation and RNA sequencing.


* Your knowledge and application of statistical concepts is considered a plus


* You are goal-oriented...