Scientist, Biologics

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Johnson & Johnson Innovative Medicine R&D is recruiting for a Scientist, Biologics located in Spring House, PA.

We are seeking a Scientist, Biologics to join our innovative team within Discovery, Product Development and Supply (DPDS).

Principal Responsibilities:


* Design and execute experiments to assess high-concentration properties of lead molecules, including viscosity, concentratability, stability, aggregation, and self-association.


* Set up and manage stability studies; prepare samples for biophysical analysis.


* Conduct high-throughput biophysical measurements using techniques such as, NanoDSF, GXII, Chromatography (Size Exclusion (SEC), Hydrophobic Interaction (HIC), CIC), Capillary Isoelectric Focusing (cIEF), Dynamic Light Scattering (DLS), Mass photometry.


* Execute methods of automation workflows: execute methods on Liquid Handlers for sample preparation (mixing, dilution, plate transfer, plate mapping).


* Independently interpret and communicate experimental results to program teams and senior management.


* Innovate and implement new techniques to assess developability and biophysical characteristics of therapeutic candidates.


* Optimize biophysics characterization workflows to improve throughput and data quality.


* Serve as a Biophysics representative on multidisciplinary project teams, contributing scientific insights and strategic direction.

Qualifications:


* A minimum of a Bachelor’s degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is required.  Master degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is preferred.


* A minimum of 5 years of relevant industry experience with a B...