Scientist, Bioanalysis – Target Engagement

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Pharmacokinetics & Pharmacometrics

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Scientist, Bioanalysis – Target Engagement to be onsite in Spring House, PA.
 

Purpose:
The Bioanalytical Discovery and Development Sciences (BDDS) organization develops, validates, and conducts bioanalytical sample analysis across the entire J&J Innovative Medicines (JJIM) R&D portfolio from discovery through development.

 We are looking for an accomplished and dedicated Scientist to design and perform target engagement assays within BDDS for Johnson & Johnson portfolio projects spanning all modalities and therapeutic areas from nonclinical studies to post-market clinical development.

You will be responsible for:


* Conduct receptor occupancy method qualification and bioanalysis using multi-parameter flow cytometry of samples supporting preclinical and clinical studies to assess target engagement of therapeutics in J&J developmental pipeline.


* Work in a regulated GLP/GCLP environment under limited supervision with a high level of autonomy, encouraging a collaborative and inclusive environment.


* Promote assigned project activities through hands-on data generation, quality control (QC) and data analysis.


* Use advanced computer software packages to collect, analyze, and interpret flow cytometry data.


* Set priorities for experimental work to ensure adequate progress of team projects and objectives.  Ensure laboratory efficiency as well as compliance with good laboratory practices and other regulatory guidelines.


* Author assay checklists, work instructions, standard operating procedures (SOPs), and technical reports,


* Mentor more junior colleagues in techniques, processes, and responsibilities.


* Actively participate in internal seminars...