Senior Principal Scientist, Cellular & Molecular Toxicology/Translational Safety

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Nonclinical Safety

Job Category:
Scientific/Technology

All Job Posting Locations:
San Diego, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Principal Scientist, Cellular & Molecular Toxicology/Translational Safety to be located in San Diego, CA or Spring House, PA.

Purpose: The Senior Principal Scientist will serve as an integral member of the Cellular & Molecular Toxicology/Translational Safety team in Translational PK/PD & Investigative Toxicology (TPPIT) and Preclinical Sciences & Translational Safety (PSTS) through the evaluation, integration, and application of conventional & complex model systems for investigations arising from target knowledge and toxicity issues during the drug development process.

This scientist will lead predictive investigative toxicity studies through the design and supervision of scientific and technical activities.

The Sr Principal Scientist will be responsible for communicating predictive investigative screening plans and updates to PSTS issues teams, project teams, and global leadership in partnership with the Global Lead of Cellular & Molecular Toxicology.

You will be responsible for:


* Lead efforts to build and refine robust high-throughput in vitro organ specific cellular screening workflows


* Serve as the liaison between High throughput screening, Data Sciences, In Silico Modeling and Preclinical Safety Teams


* In collaboration with External Scientific Innovation (Business Development) evaluate external environment to identify new technologies, platforms & CROs with novel, cutting edge applications to in vitro toxicology


* Partner with members of Translation Safety & DPDS functional groups to oversee the conversion of mechanistic cellular, molecular & biochemical toxicology assays into high throughput predictive screening assays
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