Principal Scientist, Viral Vectors (Cell and Genetic Medicines Discovery)

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biological Research

Job Category:
Scientific/Technology

All Job Posting Locations:
Cambridge, Massachusetts, United States of America

Job Description:

About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 
Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Viral Vectors (Cell and Genetic Medicines Discovery) to be located in Cambridge, MA.

Purpose:

We are seeking a highly motivated and experienced scientist to join our CAR-T cell therapy discovery efforts as a Principal Scientist.

In this role, you will play a key part in advancing our research initiatives by leveraging your expertise in viral vectors and molecular biology.  This position presents a unique opportunity to contribute to groundbreaking research in CAR-T cell therapy.

If you are passionate about advancing scientific discovery and possess a collaborative mindset, we invite you to apply!

You will be responsible for:


* Utilize your extensive knowledge in vector engineering, virology, and molecular biology to drive groundbreaking research in our cell therapy platform and pipeline development.


* Design, develop, and implement novel methodologies for vector targeting, packaging, and analytical characterization, including assays for vector quantification, potency, and purity.


* Lead efforts in troubleshooting and refining viral vector quantification techniques such as PCR-based assays, flow cytometry, and vector copy number (VCN) analysis, ensuring robust and reproducible data.


* Drive continuous improvement of vector production platforms, including titers, purity, and scalability, to enhance overall process efficiency.


* Maintain expertise and provide innovative solutions to complex research challenges


* Initiate and foster collaborative projects with internal cross-functional teams, external partners, and academic institutions to accelerate innovation and knowledge sharing.


*  Present complex data insights to diverse audiences, including r...