Science and Matrix Lead in the environment of Advanced Cell-based Assays for Drug Discovery (m/f/d)

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The Position

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.

At pRED, we are united by our mission to transform science into medicines.

Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

 The position is located in the Immune  and Cell Biology Department, within the Discovery unit  of pRED’s Large Molecules Research, where the discovery and development of next generation biotherapeutics is the primary focus.

We closely collaborate with disease therapeutic areas and other functions to convert therapeutic hypotheses into innovative therapeutics.

In this environment, we are seeking an experienced Science and Matrix Leader (m/f/d) with a strong scientific background in immune and cell biology, and a specific focus on immunology, neuroscience and/or ophthalmology.

The role requires significant industrial experience in drug discovery and development, encompassing the entire journey from target assessment to Entry into Human.  You will expertly lead cross-functional teams, contribute to portfolio projects, and drive the implementation of cutting-edge cell-based functional assays to discover and characterize large molecule-based therapeutics.

 

The opportunity 


* You will lead and inspire highly engaged cross-functional matrix teams, foster effective collaboration, and cultivate trusting relationships with internal and external partners


* You will be responsible for defining the cellular assay strategy and oversee data analysis for mode-of-action elucidations and in vitro lead selection in portfolio projects, with a particular focus on advanced, physiologically relevant human model systems


* You will conceptually develop and set up novel functional cellular assays in the fields of Immunology, Oncology, Neuroscience and Ophthalmology, employing cutting-edge assay read-out technologies including flow cytometry and advanced fluorescence microscopy

Your Profile


* Extensive industrial experience in large-molecule drug discovery, in particular leading cell-based assay development for therapeutic candidate selection in physiologically relevant model systems, including primary cells, iPSCs, organs-on-a-chip, and organoids


* Solid experience in  assay readout technolog...