Senior Manager Operations COE USP

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Supply Chain Manufacturing

Job Sub Function:
Manufacturing Pharmaceutical Process Operations

Job Category:
People Leader

All Job Posting Locations:
Leiden, South Holland, Netherlands

Job Description:

Senior Manager, Center of Expertise – Upstream Processing

Are you a transformational leader with a passion for innovation and operational excellence? Do you thrive in dynamic environments and enjoy empowering teams to deliver impactful results? If so, we invite you to explore an exciting opportunity to shape the future of biopharmaceutical manufacturing!

About the Role

We are seeking a Senior Manager to lead our Center of Expertise (COE) in Upstream Processing at our ground breaking biopharmaceutical facility in Leiden, the Netherlands.

Reporting to the Director of Upstream Processing, you will guide a team of experts dedicated to driving strategic improvements, optimizing production processes, and ensuring the highest standards of safety, quality, and compliance.

Your leadership will be instrumental in advancing our manufacturing capabilities, introducing new products, and encouraging a culture of continuous improvement and innovation.

Key Responsibilities



* Lead and inspire a high-performing team of engineers and supervisors passionate about upstream process, equipment, and quality initiatives.


* Set clear objectives aligned with business goals, and provide coaching and support to ensure team success.


* Collaborate cross-functionally with departments such as Downstream Processing COE, Make Asset Management (MAM), Quality Assurance, Manufacturing Science & Technology (MSAT), and R&D to deliver impactful projects on time and within budget.


* Supervise key performance indicators to ensure excellence in safety, quality, reliability, and financial performance.


* Drive operational efficiency in Upstream through data-driven improvements in yield and performance, demonstrating deep process and technical expertise.


* Own the introduction of new biopharmaceutical products, ensuring upstream process and equipment readiness.


* Maintain validated states of processes and equipment in compliance with Good Manufacturing Practices (GMP).


* Champion a LEAN culture through Root Cause Problem Solving, Gemba walks, and process observation.


* Promote diversity, equity, and inclusion, fostering a team culture that reflects and respects the communities we serve.

Quali...