Experienced Scientist, Viral Vector Downstream Process

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Experienced Scientist, Viral Vector Downstream Process to be located in Spring House, PA.

Purpose:

The Experienced Scientist, Viral Vector Downstream Process position in the Cell Therapy Platform & Discovery group of Therapeutics Discovery offers an exciting opportunity to help develop novel Cell & Gene Therapies for unmet medical needs.

We are investigating the use of engineered viral vectors for ex vivo and in vivo gene delivery to T cells to treat cancer.

We are seeking a highly motivated downstream process scientist to develop and implement vector purification strategies to enable preclinical studies.

Do you have industry experience with downstream viral vector process development and the ability to thrive in a cross-functional team? Come join us in our mission to build the next generation of Cell & Gene Therapies for Oncology.

You will be responsible for:


* Design, optimize, and execute downstream purification processes to improve yield, purity, and stability of lentiviral vectors (LVV)


* Independently operate and maintain chromatography and filtration systems (e.g., TFF, depth filtration) for virus purification


* Collaborate with stakeholders to ensure timely delivery of purified, quality-controlled vector lots to support preclinical studies


* Maintain detailed records for vector productions and process development experiments to ensure traceability and data integrity


* Contribute to a collaborative, creative, and rigorous culture of scientific discovery

Qualifications:


* BS or MS in Biological Engineering, Chemical Engineering, Virology, Biology, or related field with 2+ years of related experience is required.

Industry experience is preferred.


* Experie...