Principal Scientist, Translational PK/PD

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Pharmacokinetics & Pharmacometrics

Job Category:
Scientific/Technology

All Job Posting Locations:
La Jolla, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Translational PK/PD to be located in Spring House, PA or La Jolla, California.

Purpose: We are looking for a Pharmacokinetics Project Leader to join our Translational Pharmacokinetics, Pharmacodynamics and Investigational Toxicology (TPPIT) group, part of Preclinical Sciences and Translational Safety (PSTS) organization.

The successful candidate will assume a leading role in driving Non-Clinical PK, ADME and PK/PD strategy and execution to enable timely recommendations for discovery programs, drive preclinical development through IND/CTA filing, and support non-clinical and translational PK deliverables for clinical programs. 

You will be responsible for:


* Apply relevant pharmacokinetics (PK) principles, drive relevant experiment and modeling strategy, and integrate PK/ADME/PD data with pharmacology and toxicology profiles to effectively inform program strategy and decisions.


* Develop a deep understanding of the program biology/pharmacology and be an active partner on project teams, providing scientific leadership in the design and analysis of key experiments.


* Work closely with cross-functional teams, providing technical direction in supporting program decisions, compound development plans, and regulatory submissions.


* Author relevant sections of internal and regulatory submission documents and reports.


* Engage our global TPPIT and PSTS functional areas to ensure the best science is used to support programs.


* Work across multiple therapeutic areas and modalities (cell, proteins, ADCs, peptides, small molecules and RNA), and represent the program and TPPIT function at project review, p...