Director, Biomarker - Aging and Metabolism

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Translational Discovery & Development Biomarkers

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:
 

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Director, Biomarker - Aging and Metabolism to be in Spring House, PA. 

Purpose: 
This individual will play a critical role in driving biomarker strategy and advancing translational research efforts to support drug discovery and development.

This position leverages deep expertise in preclinical and clinical biomarkers to accelerate the development of novel therapeutics targeting age-related degenerative diseases, including cardiovascular pathology, thrombosis, and sarcopenic obesity.

Additionally, this role contributes to Johnson & Johnson therapeutic strategies across neuroscience, immunology, and oncology.
 

You will be responsible for:
•    Biomarker strategy to support sarcopenic and aging-related diseases, collaborating across J&J’s Cross-Therapeutic Area (TA) Small Molecule, Biologics, and MedTech teams.
•    Drive biomarker development efforts for early- and late-stage drug candidates, ensuring robust clinical translation.

 
•    Provide scientific and strategic leadership, supporting cross-functional teams and external research collaborators.

 
•    Oversee preclinical and clinical biomarker implementation, integrating cross-TA exploratory efforts to evaluate novel assets and repurpose J&J pipeline candidates.

 
•    Biomarker support for the regulatory filing of macitentan 75 in pulmonary arterial hypertension.
•    Maintain scientific leadership, fostering innovation, collaboration, and visibility through publications, external engagement, and strategic partnerships. 
•    Strategic Impact: The Biomarker Director – Aging & Metabolism plays a vital role in shaping preclinical and clinical development strategies t...