Principal Scientist, Human Genetics (African Genomics Program)

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The Position

A healthier future.

It’s what drives us to innovate.

To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That’s what makes us Roche. 
 

The Opportunity

Roche Africa is seeking a Principal Scientist, Human Genetics (African Genomics Program) to join our team.

Are you ready to accelerate the application of African genomics to advance biological understanding and highlight novel therapeutic and biomarker strategies? The Genentech/Roche African Genomics Program invites applications for a Principal Scientist position focused on African genomics.

Join us to leverage our extensive genetic, genomic, proteomic, and clinical data repositories with a focus on unique datasets generated through the Roche African Genomics Program.

Drive innovative research strategies that allow us to describe the genetic basis of disease risk and therapeutic response, and to support patient stratification.

Collaborate with recognized scientific leaders in industry and academia to make breakthrough healthcare solutions a reality. 

Key Challenges


* Spearhead analysis of genetic and genomic data gathered from African and African-descent populations to uncover novel biology, in close collaboration with our academic collaborators and with the human genetics and computational teams within Roche


* Identify and characterize genetic disease risk, progression, and therapeutic responses in African- and African-descent populations


* Utilize large-scale experimental and computational capabilities, including AI/ML, to place genetic findings in their functional context.


* Implement research strategies to translate these insights into novel opportunities for therapy, prevention and diagnosis


* Lead efforts in target identification, causal inference, biomarker discovery, and clinical strategies, working closely with our research and clinical development teams to prioritize and advance targets into therapeutic development.


* Contribute to a collaborative community involving research biology, clinical development, translational medicine, and computational sciences teams.

Who You Are as an Ideal Candidate


* You are a PhD with a strong focus on statistical genetics, genetic epidemiology, or related fields, and strong proficiency in the development and/or application of statistical methods


* Strong computational skills, including...