Associate Scientist, Cell Therapy Process Development

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
US026 PA Spring House - 1400 McKean Rd

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.   Visionaries like you work on teams that save lives by developing the medicines of tomorrow. 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Associate Scientist, Cell Therapy Process Development to be in Spring House, PA.

Purpose:

We are looking for an energetic and highly motivated Associate Scientist candidate with demonstrated expertise in autologous cell therapy process development.

The successful candidate will focus on the late-stage process development of autologous cell therapies with an emphasis on process improvement, life-cycle management, and tech transfer, enabling the advancement of these breakthrough treatments for hematological and solid tumor malignancies.

S/he will be tasked with integration of new equipment/technologies, unit operation development and route cause investigation, resulting in transformative manufacturing processes with enabling COGs ranges for cGMP Manufacturing.

The successful candidate will work as part of a cross-functional team supporting clinical programs and commercial production, focused on CMC development.

You will be responsible for:


* Leverage own experience in cell therapy process development to guide autologous platform and process development efforts


* Design and lead the execution of phase-appropriate process development studies identifying process parameters and appropriate ranges to be assessed for optimal experimental design of the study


* Collaborate with and participate in cross-functional teams to facilitate BLA enabling workstreams, BLA submission, commercial launching, and post-approval activities


* Identify, critically assess and evaluate opportunities to improve manufacturing outcomes such as improving process robustness, manufacturing success rate, product quality of final product, and reducing COGs


* Utilize phase-appropriate process development strategies to ident...