Principal Scientist, Clinical Pharmacology

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Pharmacokinetics & Pharmacometrics

Job Category:
Scientific/Technology

All Job Posting Locations:
Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Clinical Pharmacology to be in Raritan, NJ; Titusville, NJ; or Spring House, PA.

Purpose:
The Principal Scientist, Clinical Pharmacology will focus on Established Products applying clinical pharmacology knowledge and strategy to manage an array of established products.

This includes the design of clinical pharmacology studies or clinical pharmacology components of clinical studies, pharmacokinetics/pharmacodynamics analyses and reporting, and application of principles of model-informed drug development (MIDD), with guidance from senior CPP leaders, to products.

With oversight, the Principal Scientist, Clinical Pharmacology may function as the Clinical Pharmacology lead on Compound Development Teams (CDT,) working in collaboration with cross-functional team members (e.g., Statistics, Pharmacometrics, Clinical, Regulatory etc.) on all clinical pharmacology aspects of the assigned programs. 
 

You will be responsible for:
•    Design and implement scientifically robust clinical pharmacology strategies for compounds within the established product portfolio.
•    Supply compound development strategy via application of quantitative methods to integrate knowledge of nonclinical data (e.g., metabolism, BCS classification, pharmacology, safety), PK, PD (e.g., biomarker, efficacy, and/or safety), subject characteristics, disease states, competitive landscape, and drug interactions to influence go/no go decisions, support subject sub-population, dose and dosage regimen selection, and optimize study designs throughout drug development.
•    Translate quantitativ...