Principal Scientist, Toxicology

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Nonclinical Safety

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Toxicology in Spring House, PA.

Purpose: This Principal Scientist in Nonclinical Safety and Submissions, a department in the Preclinical Sciences and Translational Safety (PSTS) organization within Janssen Research & Development, supports nonclinical safety evaluation in late discovery and development for various therapeutic areas.

You will be responsible for:


* Subject matter expertise in safety pharmacology


* Design of in vivo general toxicology studies for biologics, small molecules, and other modalities.


* Integrated scientific data interpretation and critical report review for general toxicology and safety pharmacology studies.


* Oversee and monitor contracted in vivo toxicology and in vitro/in vivo safety pharmacology studies in compliance with Good Laboratory Practices (GLPs) and animal welfare regulations, following company policies and standard operating procedures.


* Engagement in multi-disciplinary teams within PSTS and close collaboration with nonclinical project representatives to provide scientific and technical expertise on drug development programs.


* Participate in issue-resolution teams through active engagement in scientific discussions and the shaping of strategies designed to support and inform critical development decisions.


* Provide strong scientific input regarding potential mechanisms of toxicity in molecular pathways and propose appropriate follow-up.

Maintain up-to-date knowledge regarding innovative approaches in toxicological research.


* Work independently, foster constructive cross-functional collaborations with both internal and external partners, and be able to prioritize workload in alignment with pipeline prior...