Principal Scientist, Lentivirus Upstream Process

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
US026 PA Spring House - 1400 McKean Rd

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are seeking a highly motivated and experienced scientist to join our Lentivirus Small Scale PD team as a Principal Scientist.

You will be responsible for:


* You will integrate into the upstream process development team and lead, contribute, and advance process development of lentiviral vector-based products for CGT within DPDS, API.


* You will have a meaningful role in the planning, prioritization, innovation, and execution of early or late phase lentiviral projects.


* You will identify and conceptualize new ideas, designing, planning and leading experiments, prioritizing areas of focus based on business objectives, and analyzing complex issues by problem-solving and turning solutions into reality.


* You will be responsible for interpreting experimental data, and then summarizing and reporting the findings to the project team, generating technical documents, and when applicable, presenting to senior management.


* Along with cell therapy process subject matter experiments, you will interact and work with internal or external GMP clinical or commercial manufacturing sites.

Qualifications:

Required:


* BS or MS degree in Chemical Engineering, Biomedical Engineering, Biological Sciences, Chemistry, Biochemistry, or other equivalent and background with 6-8 years of experience is required; or a PhD with 4+ years of post-doctoral and/or relevant industry experience is highly preferred.


* Broad knowledge in viral vector process development, preferably upstream process development, and good understanding of cell culture parameters.


* Hands-on experience with aseptic techniques, cell culture in shake flasks, Wave bioreactors, and bioreactor systems, and cell counting/monitoring methods.


* Highly organized, meticulous, and ...