Associate Scientist II, In Vitro Display

At Johnson & Johnson, we believe health is everything.

Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
Cambridge, Massachusetts, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Johnson & Johnson is currently seeking an Associate Scientist II, In Vitro Display located in Cambridge, MA.

We are seeking an outstanding Associate Scientist for our protein engineering and in vitro discovery group, who can support the development, implementation, and utilization of phage naïve or immune libraries for antibody discovery, or other emerging molecular optimization techniques to support the development of biologics (multi-specific antibodies, CAR-T, ADCs, etc.) in various disease areas.

 The position will offer an exciting opportunity to engage in the discovery and molecular engineering of biotherapeutics while also developing new processes and technologies for biologics discovery.

 This role will also include portfolio project leadership and interaction with world-class scientists in different therapeutic areas, including Oncology, Immunology, Metabolic Diseases, Neurology, and Infectious Diseases.

Principal Responsibilities:


* Perform and optimize in vitro display techniques such as phage display and yeast display for molecule discovery and selection.


* Conduct experiments involving DNA/RNA library construction, DNA purification, protein expression, purification, and characterization.


* Execute assays to evaluate the binding, off-rate, and functionality of selected candidates (flow cytometry, ELISA, Octet, etc.).


* Analyze, interpret, and document experimental data while maintaining accurate and detailed records.


* Collaborate with cross-functional teams to support project objectives and timelines.


* Contribute to troubleshooting, protocol development, and the continuous improvement of laboratory workflows.


* Prepare technical reports, presentations, and summaries for internal discussions and ex...