Scientist Process

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Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
CH008 Cilag AG, Schaffhausen

Job Description:


* Scientist Process Team (Process Design Sub-Team)
Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, Biotherapeutic’s Drug Product Development & Delivery organization, located in Schaffhausen, Switzerland.
At J&J Innovative Medicine, we are working to create a world without disease.

Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us.

We bring together the best minds and pursue the most promising science.
The Scientist in Drug Product Development & Delivery (DPD&D) Process Development team will work in conjunction with development teams to support program/project needs.

The candidate will independently lead under supervision, design and perform development and engineering activities in support of fill-finish activities for Biologics (e.g.

monoclonal antibodies, fusion proteins, bi-specifics, other therapies, etc).
Key Responsibilities:


* Act as program/project PD Lead and Support the design of laboratory experiments in collaboration with project teams.


* Uses underlying physical, chemical, and biological principles to identify the mechanisms and kinetics governing process and product performance and scale up and achieve target process performance at all scales.


* Develops fundamental understanding of large molecule parenteral process unit operations on physical/chemical/biological product quality attributes, specifically freeze/thaw, mixing, filtration, filling process steps and PAT based experiments.


* Develops and uses lab based “scale-down” models to evaluate process parameters and ranges and builds knowledge of “scale up” of unit operations to confirm or modify understanding of critical and key parameters.


* Evaluates the suitability of manufacturing processes to existing product, process, and materials platforms and vice versa.


* Works with other development teams and commercial and clinical supply chain to conduct in depth reviews of process performance data to establish/refine and drive process improvements.


* Opportunity to develop process engineering skills including the use of multi-physics s...