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Lab Technician

A neurodegeneration research laboratory in the Department of Neurology at the University of Pittsburgh is seeking a highly motivated individual for a full-time position as a Laboratory Technician (Research III).

Our research program investigates protein and enzyme changes in brains of people affected with Alzheimer's disease (AD) and traumatic brain injury (TBI) using tissue samples in conjunction with neuroimaging and biomarker measures.

Additionally, the laboratory also utilizes rodent models of AD and TBI, to probe mechanistic pathways and test, preclinically, promising therapeutics.

All projects involve sophisticated histological and biochemical techniques for assaying human and rodent brain tissue.

Position Description: The technician will be responsible for performing biochemical assays, rodent surgeries, and general laboratory maintenance.

Post-baccalaureate degree is the minimum requirement.

Successful candidates will be experienced in rodent surgery, molecular biology techniques including DNA and RNA isolation, genotyping, protein assays, ELISA, Western blotting, and enzyme activity assays on human and rodent brain tissue samples.

The Technician will work closely with the Laboratory Manager to monitor an in-house transgenic mouse colony, perform rodent surgery, and develop new laboratory techniques.

General lab maintenance responsibilities include preparing solutions for assays, assisting in inventories of chemicals, laboratory equipment, and brain tissue samples, and maintaining laboratory records and study protocols.

Strong organizational, planning, writing and communication skills as well as proficiency in computer software (Word, Excel, PowerPoint, Adobe products, statistical software) are critical.

Equivalent relevant work experience may be substituted for degree requirement.

Experience in chemistry, biological sciences or related field, with proficiency in biochemical and molecular biology techniques including DNA and RNA isolation, genotyping, protein assays, ELISA, Western blotting, and enzyme activity assays.

Experience with transgenic mice and ability to perform small animal surgeries in a preclinical setting is important.

Proficiency in computer software (Word, Excel, Powerpoint, Adobe products, statistical software) is required.





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